Who can enter
This study is for:
- Children and adults who have received an allogeneic stem cell transplant during their childhood.
- The stem cell transplantation must be at least 5 years ago.
Goal
The goal of this study is to investigate what factors are important for a good blood production, or poor blood production, years after transplantation.
Background
Hematopoietic stem cells are cells that produce blood. During a hematopoietic stem cell transplantation, the patient’s stem cells are replaced by stem cells from a healthy donor. Stem cell transplantation is a live saving therapy for various diseases.
After transplantation, the patient’s blood is produced by stem cells from the donor. This donor may be much older, or much younger, than the recipient. It is still unknown what long-term effects this has on blood production. In this study, we want to investigate hematopoietic stem cells and blood production, years after transplantation.