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Thomas Blom

PhD Student
Thomas Blom

Diagostic and therapeutic use of MIBG in neuroblastoma

In this project the focus is on diagostic use of MIBG for imaging. We study the uptake and retention of MIBG in vitro in a panel of cell lines. The contribution of the norepinephrine transporter and the vesicular transporters are studied. Concordance and discordance of MIBG uptake in MIBG avid tumors will be evaluated with aim to elucidate underlying biological factors.