Our research is focused on two main topics: pharmacogenomics and pharmacokinetic (PK) / pharmacodynamics (PD) modeling. We are studying the role of genetic variants in treatment response and susceptibility to toxicity in pediatric oncology. Also, we want to integrate genetic variants in PK/PD models of classical chemotherapy as well as novel treatments (e.g. immunotherapy) to study their effect on pharmacokinetics and pharmacodynamics in children. With our research we hope to contribute to precision medicine and be able to deliver personalized therapies to children with cancer.
Knowledge & experience
- Pharmacokinetic/pharmacodynamic modeling
2012-2019 Pharmacy BSc/MSc (Utrecht University)
2019-2021 Pharmacist, Princess Máxima Center for Pediatric Oncology
2021-present PhD Candidate Huitema Group