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Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities
mei 2023
Irene, Paassen, et al
Oncogene
Multi-dimensional profiling of hepatoblastomas and patient-derived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and identifies pan-hepatoblastoma drug sensitivities
jan. 2023
Thomas, Kluiver, et al
bioRxiv
Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label treatment
feb. 2022
Christian K, Hirt, et al
Cell genomics
EWSR1-WT1 Target Genes and Therapeutic Options Identified in a Novel DSRCT In Vitro Model
dec. 2021
Margit, Bleijs, et al
Cancers 2021, 13(23), 6072
The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma