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Frank van Leeuwen

Principal Investigator
Frank van Leeuwen
Frank van Leeuwen
Dr. Frank van Leeuwen leads a research group in the Princess Máxima Center. His team focuses on genetic aberrations that lead to pediatric acute lymphoblastic leukemia.

Publications

84 publications in total

  • Reversal of IKZF1-induced glucocorticoid resistance by dual targeting of AKT and ERK signaling pathways

    • sep. 2022
    • Miriam, Butler, et al
    • Frontiers in Oncology

  • Oncogenic TYK2P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade

    • jan. 2022
    • Katharina, Woess, et al
    • Haematologica

  • Clonal dynamics in pediatric B-cell precursor acute lymphoblastic leukemia with very early relapse

    • jan. 2022
    • Željko, Antić, et al
    • Pediatric blood & cancer

  • BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway

    • dec. 2021
    • Miriam, Butler, et al
    • Blood

  • Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations

    • dec. 2021
    • Željko, Antić, et al
    • Haematologica
View all publications