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Freek Manders

PhD student
Freek Manders
Freek Manders
Characterizing processes that shape the mutational landscapes in pediatric cancer
The aim of my PhD project is to identify and characterize the mutational processes that cause somatic mutations in pediatric cancer. Additionally, I am investigating the accumulation of somatic mutations during embryonic development
Phone 088 97 29 000
  • Mutation accumulation in mtDNA of cancers resembles mutagenesis in normal stem cells

    • dec. 2022
    • Freek, Manders, et al
    • iScience
  • A recurrent somatic missense mutation in GNAS gene identified in familial thyroid follicular cell carcinomas in German longhaired pointer dogs

    • dec. 2022
    • Yun, Yu, et al
    • BMC Genomics
  • Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes

    • aug. 2022
    • Michael T, Meister, et al
    • EMBO molecular medicine
  • Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo

    • feb. 2022
    • Karlijn A.L., Hasaart, et al
    • iScience
  • MutationalPatterns

    • feb. 2022
    • Freek, Manders, et al
    • BMC genomics
View all publications