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Stem cell transplantation is used to treat different malignant hematologic diseases and non-malignant conditions, such as leukemias, lymphomas, solid tumors and immunodeficiencies. This treatment consists of several phases, and it is tailored to each patient. At the core of the treatment is a transfusion with donor’s stem cells, which should stimulate recovery of patient’s immune system.
My project focuses on understanding this recovery – the how and why. I am investigating how the immune system recovers from the donor’s stem cells, what factors impact this recovery, and what makes this process so unique to each patient. Understanding our patients' recovery process could allow us to timely intervene and make better therapy decisions. Ultimately that could improve overall therapy success, and better the life quality of our patients.