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Ilse Timmerman

Postdoc
Ilse Timmerman
The metastatic bone marrow niche in Neuroblastoma

Our aim is to identify microenvironmental factors that contribute to therapeutic resistance in Neuroblastoma. We specifically focus on the main metastatic site; the bone marrow, as it are the residual, therapy resistant tumor cells in bone marrow that are a main cause for relapse. Ultimately, we aim to identify targets for combination therapies that act on the bone marrow microenvironment to enhance therapy sensitivity of the metastasized neuroblastoma cells, preventing their emergence as relapsed disease.

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