Josef Vormoor received his research MD from Münster University for his work on childhood AML. He gained further research experience as a postdoc in John Dick’s lab at the Hospital for Sick Children in Toronto, working on normal and leukemic hematopoietic stem cells. He then established his own research group on childhood ALL at the University Children’s Hospital in Münster. In 2006, he moved to Newcastle, first as Professor of Clinical Pediatric Oncology, from 2007 as Sir James Spence Professor of Child Health and since 2013 as Director of the Northern Institute for Childhood Cancer. His research covers mechanism of leukemic stemness, communication of the leukemic cells with their microenvironment and preclinical and early clinical drug development for childhood leukemia.