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Jurrian de Kanter

PhD student
The origin of Hodgkin’s lymphoma
Phone 088 97 25 186

I will be working on childhood Hodgkin’s lymphoma. We want to optimize and expand the FACS protocol that has been set up by the Holstege group to sort tumor cells and separate them from the microenvironment. This will allow us to perform whole genome sequencing on pure tumor cells to characterize the genetic aberrations, and single-cell RNA-sequencing to study the interactions between the tumor cells and its microenvironment, adding new insight into the extensive immune cell presence in this tumor. Furthermore, I will collaborate with Axel Rosendahl Huber and Eline Bertrums and assist in their project that investigates the genetic aberrations and signatures in second cancers.

  • Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

    • nov. 2022
    • Anne Margriet, Heijink, et al
    • Nature Communications
  • Whole-genome sequencing and mutational analysis of human cord-blood derived stem and progenitor cells

    • jun. 2022
    • Axel, Rosendahl Huber, et al
    • STAR protocols
  • Elevated mutational age in blood of children treated for cancer contributes to therapy-related myeloid neoplasms

    • jun. 2022
    • Eline J M, Bertrums, et al
    • Cancer discovery
  • Abstract A37: Single-cell RNA sequencing reveals that childhood classical Hodgkin Lymphoma resembles normal inflammation except for T cell exhaustion

    • jun. 2022
    • Jurrian K., de Kanter, et al
    • Blood cancer discovery
  • MutationalPatterns

    • feb. 2022
    • Freek, Manders, et al
    • BMC genomics
View all publications