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Lieke van Zogchel

PhD Student
Liquid biopsies in neuroblastoma


In this project we finalize the prospective validation of the use of a panel of qPCR-RNA markers for BM and blood for High-risk neuroblastoma.

We further investigate the use of cell free DNA and RNA for tumor detection, response evaluation and early recurrence detection.

  • Cell-Free RNA from Plasma in Patients with Neuroblastoma: Exploring the Technical and Clinical Potential

    • mrt. 2023
    • Nathalie S.M., Lak, et al
    • Cancers
  • Cell-Free DNA as a Diagnostic and Prognostic Biomarker in Pediatric Rhabdomyosarcoma

    • jan. 2023
    • Nathalie S M, Lak, et al
    • JCO precision oncology
  • Targeted locus amplification to develop robust patient-specific assays for liquid biopsies in pediatric solid tumors

    • jan. 2023
    • Lieke M.J., van Zogchel, et al
    • Frontiers in Oncology
  • The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples

    • jan. 2022
    • Ruben, Van Paemel, et al
    • European Journal of Cancer
  • Novel Circulating Hypermethylated RASSF1A ddPCR for Liquid Biopsies in Patients With Pediatric Solid Tumors

    • nov. 2021
    • Lieke M J, van Zogchel, et al
    • JCO precision oncology
View all publications