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Marc van de Wetering

Senior Scientist

Development of organoid technology for pediatric solid tumors.

  • Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation

    • okt. 2023
    • Lin, Lin, et al
    • Science
  • Ewing Sarcoma Single-cell Transcriptome Analysis Reveals Functionally Impaired Antigen-presenting Cells

    • jan. 2023
    • Lindy L., Visser, et al
    • Cancer Research Communications
  • Multi-dimensional profiling of hepatoblastomas and patient-derived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and identifies pan-hepatoblastoma drug sensitivities

    • jan. 2023
    • Thomas, Kluiver, et al
    • bioRxiv
  • Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes

    • aug. 2022
    • Michael T, Meister, et al
    • EMBO molecular medicine
  • Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors

    • apr. 2022
    • Bram, Herpers, et al
    • Nature Cancer
View all publications