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Ronald Stam

Principal Investigator
Since 2016, Dr. Ronald Stam leads a research group in the Princess Máxima Center. His team studies high risk forms of leukemia. By examining the genetic profile, Stam aims to discover new therapeutic targets.
Phone +31 (0) 88 972 76 72

Ronald Stam was born on December 9th 1974 in Vlaardingen, The Netherlands. After obtaining his bachelors degree in Biochemistry (Hoger Laboratorium Onderwijs, Delft, The Netherlands) and his masters degree in Molecular Biology (Leiden University, Leiden, The Netherlands), Ronald accepted his PhD for his research on MLL-rearranged Acute Lymphoblastic Leukemia (ALL) in infants in 2006 at the Erasmus MC – Sophia Children’s Hospital, Rotterdam, The Netherlands. Subsequently, Ronald was appointed research group leader in the laboratory of prof. dr. Rob Pieters at the Erasmus MC – Sophia Children’s Hospital, until 2016. In September 2016, Ronald accepted the position of Principal Investigator at the Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands. With his enthusiastic research group, currently consisting of two post-docs, four PhD-students, and two skilful technicians, Ronald continues his work on MLL-rearranged infant ALL as well as on other high-risk types of childhood acute leukemia.

In 2005, Ronald received the Basic Science Award at the 34th annual SIOP (International Society of Pediatric Oncology) meeting, Vancouver, Canada. In 2010 Ronald received an award for groundbreaking research in pediatric oncology from KIKA (Stichting Kinderen Kanker vrij) the Netherlands.

  • Combining CRISPR-Cas9 and TCR exchange to generate a safe and efficient cord blood-derived T cell product for pediatric relapsed AML

    • apr. 2024
    • Vania, Lo Presti, et al
    • Journal for ImmunoTherapy of Cancer
  • Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged acute lymphoblastic leukemia

    • sep. 2023
    • Pauline, Schneider, et al
    • Experimental hematology & oncology
  • CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in KMT2A-Rearranged Acute Lymphoblastic Leukemia

    • jan. 2023
    • Pauline, Schneider, et al
    • International journal of molecular sciences
  • A CRISPR/Cas9 engineered Mpl<sup>S504N</sup> mouse model recapitulates human myelofibrosis

    • okt. 2022
    • Fabienne R.S., Adriaanse, et al
    • Leukemia
  • Editorial

    • aug. 2022
    • Maria Teresa, Esposito, et al
    • Frontiers in Pharmacology
View all publications