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Gehonoreerde biobank verzoeken

Het overzicht van verzoeken voor de biobank die door de Biobank en Data Access Commissie en door de CRC zijn goedgekeurd vindt u hieronder.
Project number Project title  PI Date of approval
PMCLAB2018.000 The Máxima Genome Program Prof.dr. Holstege/ Dr. Tops
/ Dr. Kemmeren
16-Apr-18
PMCLAB2018.001 Dexa-dagen 2 studie (SKION OC 2017-022) Prof.dr. van den Heuvel-Eibrink 14-Nov-17
PMCLAB2018.002 MTX-FO studie (SKION OC 2018-006) Prof.dr. van den Heuvel-Eibrink 13-Mar-18
PMCLAB2018.004 Development of in vitro and in vivo research models for pediatric brain tumors Dr. Hulleman 2-Jul-18
PMCLAB2018.005 Generation of organoid models from patient-derived renal and rhabdoid tumors for the development of novel therapies Dr. Drost 19-Jul-18
PMCLAB2018.006 Generation of organoid models from patient-derived renal tumors for the development of novel therapies Dr. Drost 19-Jul-18
PMCLAB2018.007 Tracking the clonal origin of childhood acute myeloid leukemia Dr. van Boxtel 19-Jul-18
PMCLAB2018.008  Identification of translocation-specific gene expression, alternative splicing and non-coding RNA signatures in high-risk pediatric leukemias Dr. Stam 19-Jul-18
PMCLAB2018.009 Pediatric sarcoma tumoroid and single cell RNAseq analyses Prof.dr. Holstege/Dr. van de Wetering/ Dr. Janda 19-Jul-18
PMCLAB2018.010 Identification of novel drugs and drug targets for the treatment of patients harboring NUP98 gene rearrangements, a poor prognostic patient group in pediatric acute myeloid leukemia. Dr. Stam 19-Jul-18
PMCLAB2018.011 WES-KidTs (Whole Exome Sequencing in children with Kidney Tumors) Prof.dr. van den Heuvel-Eibrink 19-Jul-18
PMCLAB2018.013 Multi-platform analysis of TSC Subependymal Giant Cell Astrocytoma (SEGA) to identify novel therapeutic approaches Dr. Aronica 19-Jul-18
PMCLAB2018.014 Clinical aspects of neural crest development and anti-GD2 biomarker study for visualization and prognostification in neuroblastoma patients. Prof.dr. van Noesel 19-Jul-18
PMCLAB2018.015 Liquid-biopsy based tumor detection for rhabdomyosarcoma to improve risk stratification at diagnosis and to improve response evaluation upon treatment Dr. Tytgat 19-Jul-18
PMCLAB2018.016 Detection of cooperative and mutually exclusive genetic alterations in pediatric cancer Dr. Kemmeren 19-Jul-18
PMCLAB2018.017 SV detection/Improving detection of structural variation in pediatric cancer Dr. Kemmeren 4-Oct-18
PMCLAB2018.018 FLOWSOM analysis of AML flow cytometric data Dr. Phillipé/Dr. de Haas 4-Oct-18
PMCLAB2018.019 A comparison of new genomic technologies for detecting small structural variants Prof.dr. Holstege 28-Jan-19
PMCLAB2018.020 Cancer Immunotherapy (CIT) Cohort Dr. Dierselhuis 28-Jan-19
PMCLAB2018.021 The role of connective tissue growth factor (CTGF) as biomarker for Pediatric bone marrow failure. Dr. Leguijt 6-Dec-18
PMCLAB2018.022 Somatic mutational footprints in tumors caused by DNA repair syndromes and congenital immunodeficiency syndromes Dr. Kuiper 6-Dec-18
PMCLAB2019.024 Development of a cord blood stem cell-derived anti-AML dendritic cell vaccine: Towards powerful "anti-AML immunity" after cord blood transplantation Dr. Plantinga/Dr. Nierkens 31-Jan-19
PMCLAB2019.025 Breaking steroid resistance for T-ALL: phospho-proteomics and inhibitor testing Dr. Meijerink 18-Jul-19
PMCLAB2019.026 Mutational effects of chemotherapy on normal cells of childhood cancer survivors Dr. van Boxtel 31-Jan-19
PMCLAB2019.027 Tracing the causes and consequences of DNA damage in single hematopoietic stem cells of human Fanconi anemia patients Dr. Belderbos 31-Jan-19
PMCLAB2019.028 Unraveling pediatric AML without a known driver Dr. Noort 31-Jan-19
PMCLAB2019.029 Mechanisms of HOX-mediated Leukemogenesis in AML Dr. Adriaanse 4-Feb-19
PMCLAB2019.030 Molecular characterization of pediatric germ cell tumors: towards clinical application Dr. Looijenga 9-May-19
PMCLAB2019.031 Population dynamics of blood in Down syndrome-associated leukemia patients Dr. van Boxtel 28-Feb-19
PMCLAB2019.032 Precusor B-cell acute lymphoblastic leukaemia with Ig-MYC translocation Prof.dr. Vormoor 21-Feb-19
PMCLAB2019.033 Clonal heterogeneity and therapy resistance in Burkitt lymphoma Dr.Loeffen/ Dr. Beishuizen 21-Feb-19
PMCLAB2019.034 Mapping CLOnal evolution by Next-generation sequencing in multi-relapsed Acute Lymphoblastic B-cell precursor leukemia (CLONAL-B) Dr. Westera/Dr. de Haas 28-Feb-19
PMCLAB2019.035 Single cell analysis of pediatric medulloblastomas Prof.dr. Stunnenberg 28-Feb-19
PMCLAB2019.036 Arterial and venous thrombosis in children, teenagers and young adults treated for acute lymphoblastic leukemia/lymphoma: a joint Ponte di Legno Toxicity Working Group/ iBFM study Dr. van der Sluis 28-Feb-19
PMCLAB2019.037 A living neuroblastoma biobank with full molecular characterization Dr. Molenaar 14-Mar-19
PMCLAB2019.038 The clinical and molecular genetic spectrum of immature T- and B-cell malignancies Dr. Kroeze 14-Mar-19
PMCLAB2019.039 Bachelor thesis on effectivity of the ALL-10 treatment protocol; Research question: What is the influence of genetic abnormalities on different parameters, e.g. MRD and prednisone response in patients with T-cell acute lymphoblastic leukemia, treated by the ALL-10-protocol? Dr. van den Berg 11-Apr-19
PMCLAB2019.040 Drug resistance profiling of children with ALL Prof.dr. den Boer 11-Apr-19
PMCLAB2019.041 Digital image analysis by deep learning of Wilms tumors Dr. de Krijger 11-Apr-19
PMCLAB2019.042 Use of quality indicators in neuroblastoma treatment: a feasibility assessment Dr. Dijkstra 25-Apr-19
PMCLAB2019.043 IL-18 as diagnostic biomarker, differentiating systemic juvenile idiopathic arthritis from malignancies Dr. Leek 5-Dec-19
PMCLAB2019.044 Opzetten TMA stainings Dr. Stip 9-May-19
PMCLAB2019.045 Intensive care prevalence, morbidity, and survival in children with Wilms tumor in the Netherlands Dr. Steur 25-Apr-19
PMCLAB2019.046 Incidence, clinical presentation and clinical outcome of invasive fungal diseases in childhood acute lymphoblastic leukemia (IFD ALL-11) Dr. Bury 9-May-19
PMCLAB2019.047 The role for somatic evolution of mesenchymal stromal cells in the development of pediatric acute myeloid leukemia Dr. van Boxtel 9-May-19
PMCLAB2019.048  Immunophenotype ETP-ALL Dr. Cante - Barrett 9-May-19
PMCLAB2019.049 Onderzoek overleving van kinderen met een recidief ALL na stamceltransplantatie  Dr. Prinsze 9-May-19
PMCLAB2019.050 Surgery for Children with Cancer: Experience in a National Pediatric Oncology Center Dr. Tien Lee 20-Jun-19
PMCLAB2019.051 Impact of cytogenetic aberrations on normal hematopoietic stem cells in acute myeloid leukemia.  Dr. Belderbos 23-May-19
PMCLAB2019.052 Prognosis of AML with ‘NUP98-other’ translocations Dr. Goemans 6-Jun-19
PMCLAB2019.053 Comparison of FFPE-derived DNA and cell-free DNA from plasma in patients with pediatric rhabdomyosarcoma Dr. Lak 6-Jun-19
PMCLAB2019.054 Mechanisms of hypermutation in relapsed acute lymphoblastic leukemia in children and implications for treatment Dr. Kuiper 18-Jul-19
PMCLAB2019.055 Bulk and scRNA-seq of paediatric AML samples Prof.dr. Heidenreich 23-Sep-19
PMCLAB2019.056 Congenital cutaneous AML Dr. Goemans 18-Jul-19
PMCLAB2019.057 Ponte di Legno International Collaborative Leukemia Project Retrospective Investigation of NUT Midline Carcinoma Family Member 1 (NUTM1) rearrangements in Infants and Children with ALL Dr. Boer 18-Jul-19
PMCLAB2019.058 The Role of mRNA splicing in Leukemic Stem and Progenitor Cells in Pediatric Acute Myeloid Leukemia Dr. van der Werf 30-Aug-19
PMCLAB2019.061 Prevalence and Determinants of Tinnitus and Hearing Aid Use among 2,948 Dutch Survivors of Childhood Cancer: a DCOG Late-Effects Study Dr. Meijer 15-Aug-19
PMCLAB2019.062 Identifying a second hit in the fumarate hydratase (FH) gene Dr. Hol 15-Aug-19
PMCLAB2019.063 Single cell analysis of pediatric pheochromocytoma Dr. Brazda 15-Aug-19
PMCLAB2019.065 Assessment of cLinical outcome, Epidemiology and Risk factors of renal Toxicity (ALERT studie) Dr. Raymakers-Janssen 29-Aug-19
PMCLAB2019.066 Identifying molecular markers in peripheral blood of patients with pediatric renal tumors Dr. Tytgat 12-Sep-19
PMCLAB2019.067 The metastatic bone marrow niche in Neuroblastoma Dr. Tytgat 12-Sep-19
PMCLAB2019.068  A retrospective analysis of severely delayed methotrexate clearance in children with Acute Lymphoblastic Leukemia(ALL) Dr. Oosterom 26-Sep-19
PMCLAB2019.069 Osteonecrosis in children and adolescents with Philadelphia chromosome positive acute lymphoblastic leukemia(Phi+ALL) treated with tyrosine kinase inhibitors (TKIs) in the EsPhALL protocols: incidence, risk factors, management and outcome. Contribution to a retrospective multicenter study, within the EsPhALL trials Prof.dr. van den Heuvel-Eibrink 26-Sep-19
PMCLAB2019.070 Autologe stamceltransplantatie bij pediatrisch oncologische patiënten; “Poor Mobilisers”, Plerixafor en (PEG)filgrastim Dr. Kraal 26-Sep-19
PMCLAB2019.071 Visual impairment in children with a brain tumor detected via unstructured ophthalmology screening :  a retrospective cohort study Dr. Schouten 10-Oct-19
PMCLAB2019.073 Analysis of CD37 expression in pediatric mature B‐cell lymphomas and correlation with clinical presentation and outcome Dr. Meyer-Wentrup 7-Nov-19
PMCLAB2019.074 The bone marrow niche revisited: secretome profiling of pediatric ALL and AML Prof.dr. den Boer 7-Nov-19
PMCLAB2019.075 Neuroblastoma European Catecholamine Study Dr. Tytgat 24-May-20
PMCLAB2019.076 Physical performance in children with (supra)sellar tumors and hypothalamic dysfunction Dr. Rehorst-Kleinlugtenbelt 21-Nov-19
PMCLAB2019.077 Generation of Hodgkin’s lymphoma organoids for functional studies Dr. Meyer-Wentrup 21-Nov-19
PMCLAB2019.079 CARs for CNS-Leukemia Relapse: A retrospective international study proposal Dr. Vormoor-Burger 5-Dec-19
PMCLAB2019.080 Characteristics of the neuro-vascular unit of the pons in patients suffering from diffuse intrinsic pontine glioma and healthy children Dr. El-Khouly 5-Dec-19
PMCLAB2019.081 Identifying Minimal Residual Disease targets by FUDGE, a rapid Nanopore-sequencing based fusion-gene detection assay Dr. Westera 5-Dec-19
PMCLAB2019.082 Benign and malignant skin disorders in CCS: the LATER SKIN cohort study Prof.dr. Kremer 5-Dec-19
PMCLAB2019.084 Limbic system damage and neuropsychological outcomes in pediatric posterior fossa tumors Dr. Partanen 5-Dec-19
PMCLAB2019.085 Screening of neuropsychological impairments in pediatric brain tumor Dr. Partanen 5-Dec-19
PMCLAB2019.086 Detecting fibronectin splice-variants in osteosarcoma tumors Dr. Janda 19-Dec-19
PMCLAB2019.087 Detection of high risk cancer predisposing genes Dr. Kuiper 13-Feb-20
PMCLAB2020.088 Morphology of Burkitt lymphoma Dr. Vermeulen 16-Jan-20
PMCLAB2020.089 The contribution of surgical clips for optimizing image-guided radiotherapy in pediatric renal tumors: the Utrecht experience Prof.dr. van den Heuvel-Eibrink / Dr. Mul 16-Jan-20
PMCLAB2020.090 In-vitro models for rare pediatric cancers Prof.dr. Clevers / Dr.van de Wetering 30-Jan-20
PMCLAB2020.092 The mutational spectrum of immature T-cell malignancies Dr. Meijerink / Dr. Kroeze 30-Jan-20
PMCLAB2020.093 Full molecular characterization of the Princess Máxima Neuroblastoma cohort Dr. Molenaar /Dr. Langenberg 10-Mar-20
PMCLAB2020.094 Investigating the mutational spectrum of pediatric non-rhabdomyosarcoma soft tissue sarcomas (NRSTS) Prof.dr. Holstege /Dr. Meister 30-Jan-20
PMCLAB2020.095 Risk factors and prognosis of disseminated pediatric low grade glioma Prof.dr. Hoving /Dr. van den Bergen 30-Jan-20
PMCLAB2020.096 The feasibility to make a Neuroblastoma xenograft bearing mouse with intact immune system Dr. Tytgat 30-Jan-20
PMCLAB2020.097 Immunomonitoring: Investigation of efficacy of GM-CSF and G-CSF to activate neutrophils Dr. Tytgat 30-Jan-20
PMCLAB2020.098 Radiotherapy-related meningioma, cerebrovascular events, and cataract in childhood cancer survivors: A Dutch LATER cohort Study project Prof.dr. Kremer 30-Jan-20
PMCLAB2020.099 Health problems after 3D-planned pediatric radiotherapy: A nation-wide cohort study Prof.dr. Kremer 30-Jan-20
PMCLAB2020.100 RNAseq data from neuroblastoma. (Neuroblastoma cell of origin) Prof.dr. Clevers / Dr.van de Wetering 13-Feb-20
PMCLAB2020.101 Cataloguing and characterizing chemotoxicities of B-ALL treatment in Down syndrome children Dr. van Boxtel/ Dr. Hasaart 13-Feb-20
PMCLAB2020.102 An International Study on Pediatric PICALM-MLLT10 + Leukemias Dr. Goemans 13-Feb-20
PMCLAB2020.103 Risk factors and consequences of thyroid dysfunction after treatment for childhood cancer : filling the gaps in evidence needed for new international recommendations. The Dutch LATER cohort  thyroid dysfunction  study. (LATER THYR)  Prof.dr. Kremer/Dr. van Santen 13-Feb-20
PMCLAB2020.104 The incidence of influenza infections and risk factors for severe disease in children with cancer Prof.dr. Tissing 13-Feb-20
PMCLAB2020.105 Validation of the molecular profiling pipeline at the Princess Máxima Center within the Princess Máxima Center precision medicine program iTHER Dr. Molenaar 23-Mar-20
PMCLAB2020.106 Identification of genomic signatures predictive of AML outcome in paediatric patients Prof.dr. Zwaan 27-Feb-20
PMCLAB2020.107 Towards understanding pediatric liver tumors Dr. Peng 27-Feb-20
PMCLAB2020.108 The validation of the SARC-F child: a screenings tool in pediatric oncology Prof.dr. van den Heuvel-Eibrink 27-Feb-20
PMCLAB2020.109 Adult growth hormone deficiency in childhood cancer survivors. Prof.dr. van den Heuvel-Eibrink 18-Jun-20
PMCLAB2020.110 Metabolic syndrome in childhood cancer survivors (DCOG LATER METS study) Prof.dr. van den Heuvel-Eibrink 18-Jun-20
PMCLAB2020.111 Frailty, impaired bone mineral density, fractures and follow-up of osteonecrosis in childhood cancer survivors (DCOG LATER BONE study) Prof.dr. van den Heuvel-Eibrink 18-Jun-20
PMCLAB2020.112  Mutational dynamics between primary and relapse tumors of patients within the Princess Máxima Center precision medicine program iTHER Dr. Molenaar 3-Apr-20
PMCLAB2020.113 Creation of a Tissue Micro-Array of primary Neuroblastoma samples Dr. Molenaar 27-Feb-20
PMCLAB2020.114 Identifying the causal mechanism behind (no-known-driver) pediatric acute myeloid leukemia Dr. van Boxtel 12-Mar-20
PMCLAB2020.116 Fusion gene detection using nanopore sequencing Dr.Tops/ Dr. Monroe 12-Mar-20
PMCLAB2020.118 FFPE-derived DNA for target identification in cell-free DNA in patients with neuroblastoma Dr. Tytgat 12-Mar-20
PMCLAB2020.119 A nationwide descriptive study of genetic predisposition in children with cancer: evaluation of diagnostic processes and consequences for clinical management Dr. Kuiper/Dr. Jongmans 26-Mar-20
PMCLAB2020.120 Presence of scRNA sequencing markers in neuroblastoma patients Prof.dr. Clevers / Dr.van de Wetering 26-Mar-20
PMCLAB2020.121 Benefits and limitations of implementation of a clinical decision support system (CDSS) to optimize drug dosing in paediatric oncology patients with impaired renal function (SIGNPOST) Dr. Muilwijk 26-Mar-20
PMCLAB2020.122 Cerebrospinal fluid leakage after intradural surgery in the pediatric population – A retrospective cohort study Prof.dr. Hoving 9-Apr-20
PMCLAB2020.123 A descriptive study of gliomas in children with Li Fraumeni syndrome Dr. Jongmans 9-Apr-20
PMCLAB2020.124 Tumor-infiltrating lymphocytes in Neuroblastoma Dr.Molenaar/Dr.Tytgat/Dr.van Noesel 16-Apr-20
PMCLAB2020.125 Effects of different formulations on Standardised Uptake Value measurements in Pediatric PET imaging Dr. Merks/ Dr. de Keizer 23-Apr-20
PMCLAB2020.126 Clinical outcome of second relapsed and refractory first relapsed pediatric AML. A retrospective study within the NOPHO-DB SHIP consortium Prof.dr. Kaspers 23-Apr-20
PMCLAB2020.127 Training MRI data for development of a semi-automated MRI analysis tool; part of the  international retrospective DW-MRI rhabdomyosarcoma study project Dr. Merks 23-Apr-20
PMCLAB2020.128 Exploring the origin of extramedullary pediatric acute myeloid leukemia. Dr. van Boxtel 7-May-20
PMCLAB2020.129 Detection of cell surface antigens in rhabdomyosarcoma Dr. Janda 7-May-20
PMCLAB2020.130 Patient-derived models to study disease biology and the therapeutic potential of gene therapy in Diamond-Blackfan Anemia.   Dr. de Haas 26-May-20
PMCLAB2020.131 Longitudinal patterns of quality of life during and after cancer treatment  Dr. Partanen/ Prof. dr. Grootenhuis 25-May-20
PMCLAB2020.132 Germline PAX5 alterations in pediatric ALL Dr. Kuiper/Dr. Jongmans 25-May-20
PMCLAB2020.133 DMTR: Dutch Melanoma Treatment Registry Dr. Zsiros 22-Jun-20
PMCLAB2020.134 Characteristics and outcome of children with renal tumors in the Netherlands, the first full five years experience of national centralization in the Princess Máxima Center for pediatric oncology, a descriptive national study. Prof.dr. van den Heuvel-Eibrink 4-Jun-20
PMCLAB2020.135 Functional analyses of leukaemic lineage switches and MPALs Prof.dr. Heidenreich 4-Jun-20
PMCLAB2020.136 Extracellular vesicles in patients with neuroblastoma: standardization and characterization  Dr. Tytgat 22-Jun-20
PMCLAB2020.137 TransExpo: International Study of Childhood Leukemia and Residences Near Electrical Transformer Rooms Dr. Karim 18-Jun-20
PMCLAB2020.139 Natural history and prognostic factors of incidentelomas Prof.dr. Hoving 18-Jun-20
PMCLAB2020.141 Targeting the central nervous system in MLL-rearranged infant acute lymphoblastic leukemia Dr. Stam 18-Jun-20
PMCLAB2020.142 Pediatric brain tumor research at the Princess Maxima Center Dr. Kool 2-Jul-20
PMCLAB2020.143 Psychosocial functioning of Dutch children with cancer and their parents during the COVID-19 pandemic Prof.dr. Grootenhuis 18-Jun-20
PMCLAB2020.144 Analysis of markers of neurons in the adult human adrenal medulla Dr. Molenaar 18-Jun-20
PMCLAB2020.145 Identifying cause of therapy failure in BCR-ABL 1 positive and BCR-ABL 1-like ALL. Prof.dr. den Boer 2-Jul-20
PMCLAB2020.146 Clostridioides difficile in pediatric cancer and hematopoietic stem cell transplantation. Prof.dr. Tissing 2-Jul-20
PMCLAB2020.148 Brain tumors in pediatric patients with neurofibromatosis type 1 in care or follow-up in a national pediatric oncologic center (a cohort study). Prof.dr. Hoving 2-Jul-20
PMCLAB2020.149 Further development of kidney organoid culture: towards clinical applications Dr. Drost 2-Jul-20
PMCLAB2020.150 Filling the gaps in evidence on prevalence, risk and surveillance for thyroid nodules and thyroid cancer in childhood cancer survivors (LATER THYR II). Prof.dr. Kremer 4-Aug-20
PMCLAB2020.151 Identifying the mechanisms underlying therapy-related pediatric AML. Dr. van Boxtel 16-Jul-20
PMCLAB2020.152 Added value of ASL perfusion MRI and 1H MRS in diagnosing  and follow up of children with a brain tumor Prof.dr. Hoving 16-Jul-20
PMCLAB2020.153 Genomic analysis of myofibromatosis. Dr. Merks 16-Jul-20
PMCLAB2020.154 Cell free detection of hypermethylated RASSF1A in pediatric solid tumors. Dr. Tytgat 16-Jul-20
PMCLAB2020.155 Ponte di Legno International Collaborative Leukemia Project; Retrospective investigation of tumor genetics in children with ETV6-RUNX1 positive ALL Prof.dr. Pieters/Prof.dr. den Boer 16-Jul-20
PMCLAB2020.156 A retrospective analysis of the effect of inotuzumab ozogamicin on CAR-T cell treatment in B-cell precursor ALL. Prof.dr. Zwaan 16-Jul-20
PMCLAB2020.157 Testis Sparing Surgery in Pediatric Testicular Tumors Prof.dr. van Noesel 16-Jul-20
PMCLAB2020.158 Development of an in vitro  culture system for pre-pubertal spermatogonial stem cells. Dr. Looijenga 16-Jul-20
PMCLAB2020.160 Detection of mutational processes in acute lymphoblastic leukemia Dr. Kuiper 16-Jul-20
PMCLAB2020.161 Improving diagnostics and therapy response of TP53 aberrant ALL Dr. van Leeuwen/ Dr. Kuiper 16-Jul-20
PMCLAB2020.162 Risk and time trends of subsequent tumors after five decades of pediatric cancer treatment Prof.dr. Kremer 27-Aug-20
PMCLAB2020.163 Imaging features of hepatic sinusoidal obstruction syndrome or veno-occlusive disease in children –a pictorial essay Prof.dr. van Noesel 27-Aug-20
PMCLAB2020.164 Unraveling the immune microenvironment of ependymomas Prof.dr. Hoving 27-Aug-20
PMCLAB2020.165 Immunoglobulin and T-cell receptor rearrangement detection in RNAseq, WES and WGS datasets Dr. Tops 10-Sep-20
PMCLAB2020.168 Lineage cell tracing in histiocytosis patients Prof.dr. Heidenreich 24-Sep-20
PMCLAB2020.170 Completing the information database of Nijmegen patient samples Dr. Kuiper 8-Oct-20
PMCLAB2020.171  DWI-MRI based personalized tumor discrimination in children with renal tumors.  Prof.dr. van den Heuvel-Eibrink 8-Oct-20
PMCLAB2020.172 Impact of Conditioning, Graft Manipulation and Source on Outcomes after Transplantation for Fanconi anemia Dr. Bierings 8-Oct-20
PMCLAB2020.173 Panel-of-normals for copy number and structural variant detection in WES and WGS data Dr. Kuiper 8-Oct-20
PMCLAB2020.174 Develop and validate a pharmacokinetic model for high-dose methotrexate and quantification of the exposure-toxicity relationship in order to better predict and prevent severe methotrexate toxicity. Dr. Hanff 22-Oct-20
PMCLAB2020.175 MRI changes after proton and photon therapy for primary pediatric CNS tumors in The Netherlands. Prof.dr. Hoving 30-Oct-20
PMCLAB2020.176 Pediatric T-cell Acute Lymphoblastic Leukemia in the Netherlands: a population-based study over a 40 year period Prof.dr. Pieters 27-Oct-20
PMCLAB2020.177 Health-related quality of life and its determinants in pediatric acute myeloid leukemia Prof.dr. Grootenhuis 22-Oct-20
PMCLAB2020.178 Survival outcomes after relapse of myeloid leukemia in children with down syndrome Dr. Goemans 21-Dec-20
PMCLAB2020.179 Immunohistochemical evaluation of CD99, CXCR4, NPY-R-Y1, LINGO-1, IGF-1R, C-Kit (CD117), NOTCH-R, Occludin and Claudin-1 for fluorescence-guided surgery (FGS) of Ewing sarcoma. Prof.dr.Wijnen 19-Nov-20
PMCLAB2020.180 Registry of Chimeric Antigen Receptor T cell recipients with SARS-CoV-2 infection  Prof.dr. Vormoor 18-Nov-20
PMCLAB2020.181 Clinical course and molecular characterization of a retrospective nation-wide cohort of Dutch pediatric CNS germ cell tumors Dr. Looijenga 5-Nov-20
PMCLAB2020.182 Histological and molecular characterization of extracranial germ cell tumors: towards an optimal patient risk stratification. Dr. Looijenga 5-Nov-20
PMCLAB2020.183 ABDOMINAL NEUROBLASTOMA – Estimation of the clinical benefit of proton therapy based on literature review with validation of the Dutch single center cohort 2015-2020. Prof.dr. van Noesel 5-Nov-20
PMCLAB2020.184 Isolation of mesenchymal stromal cells and haematopoietic stem and progenitor cells from human bone marrow Prof.dr. Heidenreich 19-Nov-20
PMCLAB2020.185 CloFluBu conditioning in HCT for pediatric leukemia Dr. Bierings 5-Nov-20
PMCLAB2020.186 Time trends in incidence and survival of thyroid carcinoma in children, adolescents and young adults (0-24 years) in the Netherlands, 1990-2018 Prof.dr. van Noesel 19-Nov-20
PMCLAB2020.187 Survival of children, and adolescents and young adults (AYAs) with acute myeloid leukemia (AML) in the Netherlands Prof.dr. Zwaan 19-Nov-20
PMCLAB2020.188 The thymus as resource of mediastinal germ cell tumors.   Dr. Looijenga 19-Nov-20
PMCLAB2020.190 Identification of novel tumor-specific proteins and epitopes across pediatric tumor types Dr. van Heesch 3-Dec-20
PMCLAB2020.191 Time trends in incidence, stage at diagnosis, treatment and survival of sarcomas diagnosed in children and young adolescents (<18 years) in the Netherlands, 1990-2019 Dr. Merks 3-Dec-20
PMCLAB2020.193 Treatment with chemotherapy in (relapse/progressive) pilocytic astrocytome: a multicenter retrospective cohort study. Prof.dr. Hoving 21-Dec-20
PMCLAB2020.194 Outcome for children with acute myeloid leukemia in the Netherlands following initial treatment between 1998 and 2018 Prof.dr. Zwaan 10-Dec-20
PMCLAB2020.195 Uitkomsten van directe lijn wissels versus een lijnvrij interval na centrale lijn verwijdering i.v.m. een centrale lijn geassocieerde bloedbaan infectie in kinderoncologie patiënten. Prof.dr.Wijnen 17-Dec-20
PMCLAB2020.196 Dose-evaluation of antifungal treatment with isavuconazole in pediatric oncology patients (DEFINE) Prof.dr. Tissing 17-Dec-20
PMCLAB2021.199 Imaging of neuroblastoma and correlation with other diagnostic techniques Dr. Tytgat 7-Jan-21
PMCLAB2021.200 Cancer penetrance in patients with germline pathogenic variants in SMARCA4 Dr. Jongmans 7-Jan-21
PMCLAB2021.201 Hypothalamic function and its relation to BMI change in children with brain tumors Prof. Dr. Tissing 7-Jan-21
PMCLAB2021.202 Evaluation of b-SSFP as non-contrast MRA for surgical planning of Wilms tumour surgery Prof. Dr. Wijnen 7-Jan-21
PMCLAB2021.203 Machine learning based MRI segmentation for 3D visualization in Wilms tumor planning Prof. Dr. Wijnen 7-Jan-21
PMCLAB2021.204 Improved histological and molecular characterization of pediatric central nervous system tumors Dr. Tops 21-Jan-21
PMCLAB2021.206 The role of functional imaging (FDG-PET and DW-MRI) in children and adolescents with an osteosarcoma or Ewing sarcoma Dr. Merks 21-Jan-21
PMCLAB2021.207 Communication in the AML niche and its impact on treatment response Prof. Dr. Heidenreich 4-Feb-21
PMCLAB2021.208 Risk of Central-Line Associated Bloodstream Infections in Pediatric Neuroblastoma Patients Receiving Immunotherapy Prof. Dr. Wijnen 21-Jan-21
PMCLAB2021.209 Early detection of lymphoma in CMMRD and AT patients Dr. Kuiper 4-Feb-21
PMCLAB2021.210 The transition of lymphoblastic malignancies: when does leukemia become lymphoma and vice versa? Dr. Meijerink 4-Feb-21
PMCLAB2021.211 Predictors for malignancy in children with lymphadenopathy Dr. Meyer-Wentrup 4-Feb-21
PMCLAB2021.212 MRD monitoring during maintenance in pediatric patients with acute lymphoblastic leukemia Prof. Dr. Pieters 18-Feb-21
PMCLAB2021.214 Investigating the relationship between RNA alterations and upstream genomic events in pediatric cancer Dr. Kemmeren 18-Feb-21
PMCLAB2021.215 RNA-seq based tumor classification for a broad range of pediatric cancer types Dr. Kemmeren 18-Feb-21
PMCLAB2021.216 Detection and monitoring of cell free tumor DNA in plasma of infants with KMT2A-rearranged ALL Prof.dr. Pieters 4-Mar-21
PMCLAB2021.217 Clinical relevance of a hotspot at the central venous access device tip on FDG PET-CT in pediatric oncology patients Prof.dr. Pieters 4-Mar-21
PMCLAB2021.218 Efficacy of Imatinib in ABL-class fusion positive ALL Prof.dr. den Boer 4-Mar-21
PMCLAB2021.219 Proposal for use of biobank patient materials for dedicated study related to patientcare Dr. Tops/Dr. de Haas 4-Mar-21
PMCLAB2021.220 Immunofluorescent evaluation of CXCR4, NCAM, Jagged1, GJA-1 and Cadherin11 for fluorescence-guided surgery (FGS) of Wilms tumor Prof.dr. Pieters 18-Mar-21
PMCLAB2021.221 A retrospective study on the use of CAR T-cells after Inotuzumab Ozogamicin treatment in children with relapsed or refractory acute lymphoblastic leukemia (ALL) Prof.dr. Zwaan 18-Mar-21
PMCLAB2021.222 Palliative Care in a National Pediatric Oncology Center in the Netherlands: results of the first 18 months Prof.dr. Tissing 18-Mar-21
PMCLAB2021.223 Evaluation of risk stratification based on genetic markers of ALL cases in the ALLTogether protocol Prof.dr. den Boer 18-Mar-21
PMCLAB2021.224 Retrospective analysis of treatment outcomes of acute promyelocytic leukemia in Dutch children from 2005 until 2021 Prof.dr. Kaspers 1-Apr-2021
PMCLAB2021.225 Regeneration of the human hematopoietic stem cell niche after transplantation Dr. Belderbos 1-Apr-2021