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Douwe van der Leest

Douwe van der Leest
Performing translational bioinformatics in the fight against pediatric cancer

As a member of the team "Translational bioinformatics of pediatric cancer", I’m involved in using and developing a genomic data analysis platform aiming at providing patients and their treating physician with genomic data ready for diagnostics purposes. We are in charge of detecting somatic and germline variants (SNVs, indels, CNVs and SVs) in tumor and organoid samples based on WES and RNA-seq data for diagnostics purposes. We do these analyses in a High Performance Computing environment and need WDL and Cromwell as a Service for distributing the tasks that need to run. Besides diagnostics operations, we closely collaborate with the Kemmeren group on extending and improving the available pipelines and developing new ones.

Knowledge & experience

  • Bioinformatics
  • Programming (Bash, Python, WDL, JavaScript)
  • Genetics & Genomics

Working experience
2018-2019       Bioinformatician at Limgroup B.V. | Geneticist
2019-present   Clinical Bioinformatician

BSc Biologie (Biology) | Wageningen University & ResearchWageningen University & Research
MSc Plantenwetenschappen (Plant Sciences) | Wageningen University & ResearchWageningen University & Research