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Weng Chuan Peng

Principal Investigator
Weng Chuan Peng
Weng Chuan Peng
Childhood liver cancer
Phone 088 97 290 00

We are a translational stem cell biology lab focusing on childhood liver cancer and regenerative medicine. The Peng group aims to uncover the molecular mechanism underlying the development of childhood liver cancer, develop novel therapeutics (e.g., antibodies), and establish organoid-driven technology for (pre)clinical applications.

  • Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS

    • jul. 2023
    • Ianthe A E M, van Belzen, et al
    • BMC Cancer
  • Multi-dimensional profiling of hepatoblastomas and patient-derived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and identifies pan-hepatoblastoma drug sensitivities

    • jan. 2023
    • Thomas, Kluiver, et al
    • bioRxiv
  • Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade

    • jul. 2022
    • Yinhua, Jin, et al
    • Proceedings of the National Academy of Sciences of the United States of America
  • Molecular hallmarks of heterochronic parabiosis at single-cell resolution

    • mrt. 2022
    • , et al
    • Nature
  • Long-Term Expansion of Murine Primary Hepatocyte Organoids

    • jan. 2022
    • Thomas A., Kluiver, et al
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