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Our researchgroup is dedicated to translational research in pediatric oncology, with a special focus on renal tumors and the (genetic) variation of early and late toxicity of childhood cancer through international collaboration.
Clinical syndromes linked to biallelic germline variants in MCM8 and MCM9
jul. 2025
Noah C, Helderman, et al
Human Genetics and Genomics Advances
Predisposition Footprints in the Somatic Genome of Wilms Tumors
feb. 2025
Taryn D, Treger, et al
Cancer discovery
Hallmark discoveries in the biology of non-Wilms tumour childhood kidney cancers
jan. 2025
Daniela, Perotti, et al
Nature reviews. Urology
Nephron-sparing surgery for pediatric renal tumors after centralization of pediatric oncology care in the Netherlands: Improved outcomes with 3D modeling
dec. 2024
Matthijs, Fitski, et al
Journal of Pediatric Surgery
Metabolic profiling of patient-derived organoids reveals nucleotide synthesis as a metabolic vulnerability in malignant rhabdoid tumors