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Mirjam Belderbos

Group leader / Pediatric oncologist

Understanding human hematopoietic stem cell biology 

Phone 088-9727272

As a stem cell biologist and clinician working in stem cell transplantation, I want to understand how hematopoietic stem cells produce blood and why they sometimes fail. Although hematopoietic stem cells are the most commonly used type of stem cells for therapy, the mechanisms by which they regenerate all differentiated blood cells are incompletely known. My lab uses various (single-cell) sequencing technologies to study the behavior of human hematopoietic stem cells in health, disease and therapy. Our ultimate goal is to translate fundamental understanding of hematopoietic stem cell biology into novel therapies to benefit patients. 

  • Bone marrow lymphocyte dynamics during chemotherapy in pediatric acute myeloid leukemia

    • sep. 2025
    • Joost B., Koedijk, et al
    • HemaSphere
  • Improved survival with model-based dosing of antithymocyte globulin in pediatric hematopoietic cell transplantation

    • mei 2025
    • Rick, Admiraal, et al
    • Blood advances
  • Improved survival with model-based dosing of antithymocyte globulin in pediatric hematopoietic cell transplantation

    • mei 2025
    • Rick, Admiraal, et al
    • Blood advances
  • Who owns that blood? Recontacting donors with results from genetic testing after allogeneic hematopoietic cell transplantation

    • mrt. 2025
    • Mirjam E., Belderbos, et al
    • HemaSphere
  • Increased Clonal Hematopoiesis in Long-term Survivors of Pediatric Hematopoietic Cell Transplantation

    • mrt. 2025
    • Konradin F., Müskens, et al
    • Blood cancer discovery
View all publications