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  • Dr. Meta Diekstra

Dr. Meta Diekstra

Hospital pharmacist & Clinical pharmacologist
As a hospital pharmacist and clinical scientist, I focus on advancing precision medicine for children with cancer. My work combines clinical practice with research in pharmacogenomics, therapeutic drug monitoring, and innovative drug repurposing projects. By bridging pharmacology research and clinical implementation, I aim to tailor treatments to the individual child, ensuring better outcomes in pediatric oncology care.
Phone +31 650006289
Email m.h.m.diekstra@prinsesmaximacentrum.nl


Skills & Interests

Pharmacogenomics, Clinical Pharmacology, Tyrosine kinase inhibitors, PK/PD/PGx studies


Working experience

2021-present      Hospital pharmacist/Clinical pharmacologist, Princess Máxima Center for pediatric oncology   
2020-2021        Clinical Pharmacologist (ErasmusMC Rotterdam)
2017-2020        Hospital pharmacist in training, Maastricht UMC/Zuyderland MC/Erasmus MC
2017                    PhD: ‘Pharmacogenetics of sunitinib in metastatic renal cell carcinoma’, Leiden University
2012-2017        Pharmacist/researcher, Leiden University Medical Center


Projects

  • TowardS Identifying chiLdrEN with cancer with genetic susceptibility for Cisplatinum induced hEaring loss, baseD on an international genome-wide association analysis - the SILENCED study (KiKa)
  • Repurposing of disulfiram and copper for the treatment of Ewing sarcoma (RESCUE) (KiKa)
  • PATIO study: Pharmacokinetic study on Anticancer Treatment in Infant acute lymphoblastic leukemia to support Optimal dosing (ZonMW)

BIG-registratie: 99916110017
LinkedIn: https://www.linkedin.com/in/metadiekstra/
ORCID: https://orcid.org/0000-0002-9368-3650

Publications

24 publications in total

  • De noodzaak voor hogere propofol doseringen na herhaalde sedaties voor invasieve procedures bij kinderen met acute lymfatische leukemie – een zorgevaluatie

    • nov. 2023
    • Jetske, Graafsma, et al
    • Pharmaceutische Weekblad Wetenschappelijk Platform

  • Therapeutische geneesmiddelmonitoring van kinaseremmers in de kinderhemato-oncologie

    • sep. 2023
    • Tirsa, de Kluis, et al
    • Nederlands Tijdschrift voor Hematologie

  • Ernstig acute nierschade na high-dose methotrexaat bij een patiënt met polymorfismen in ABCB1 en ABCBG2

    • mrt. 2023
    • Emma, Bernsen, et al
    • Nederlands Tijdschrift voor Oncologie (NTvO)

  • Genetic variants found in paediatric oncology patients with severe chemotherapy-induced toxicity

    • jan. 2023
    • E C, Bernsen, et al
    • Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

  • Practical Recommendations for the Manipulation of Kinase Inhibitor Formulations to Age-Appropriate Dosage Forms

    • dec. 2022
    • Emma C, Bernsen, et al
    • Pharmaceutics
View all publications