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Irene Paassen

PhD student
Irene Paassen
Irene Paassen
Epigenetic heterogeneity in rhabdoid tumors

I am a PhD student in the Drost group since August 2019. I am working on the establishment of patient-derived ATRT tumoroid development and unravelling subtype-specific differences between the distinct subtypes of malignant rhabdoid tumor. We aim to study the heterogeneity within and between rhabdoid samples implementing various techniques such as single-cell RNA+ATAC sequencing, lentiviral-based gene perturbation or high throughput drug screenings.

  • Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors

    • aug. 2021
    • Camilla, Calandrini, et al
    • Cell reports
  • In vitro Modeling of Embryonal Tumors

    • jan. 2021
    • Lars, Custers, et al
    • Frontiers in cell and developmental biology
View all publications