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Mieke Roosen

PhD student

Brain tumor organoids as models for pediatric brain tumors

Phone 088 97 25 026
Email m.m.roosen@prinsesmaximacentrum.nl

Establish human cerebral brain organoids from embryonic stem cells or induced pluripotent stem cells and use these to model ependymoma and ETMR tumors.

Publications

9 publications in total

  • BIOL-11. PRECLINICAL MODELLING OF PEDIATRIC BRAIN TUMORS USING ORGANOID TECHNOLOGY

    • dec. 2023
    • Mieke, Roosen, et al
    • Neuro-Oncology

  • Genetic and compound screens uncover factors modulating cancer cell response to indisulam

    • sep. 2022
    • Ziva, Pogacar, et al
    • Life Science Alliance

  • The oncogenic fusion landscape in pediatric CNS neoplasms

    • apr. 2022
    • Mieke, Roosen, et al
    • Acta Neuropathologica

  • MEDB-52. Organoids as preclinical models to improve and personalize disease outcome for sonic hedgehog medulloblastoma

    • mrt. 2022
    • Zelda, Odé, et al
    • Neuro-Oncology

  • ETMR-09. In vitro modelling of embryonal tumors with multilayered rosettes (ETMR) and other novel brain tumor types.

    • mrt. 2022
    • Jens, Bunt, et al
    • Neuro-Oncology
View all publications