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Renée Mulder

Renée Mulder
Renée Mulder
Clinical practice guidelines and quality of care improvement
Phone 088 97 25 193

To provide high-quality care for childhood cancer patients and survivors and to optimize their quality of life and life expectancy, clinicians must stay up-to-date with the newest scientific evidence. Clinical practice guidelines are essential in translating evidence into clinical practice, giving clinicians guidance to provide optimal care. During my PhD we have founded the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) and have established evidence-based methods to develop guidelines within pediatric oncology. The IGHG is chaired by Leontien Kremer and Melissa Hudson from the St. Jude Children’s Research Hospital in Memphis, United States and coordinated by me. I produce and assist international harmonized guidelines for the long-term follow-up care for childhood cancer survivors and fertility preservation for children with cancer. Moreover, I produce and assist the development of national and international supportive care guidelines. An important step is the dissemination of guidelines and the translation into patient materials together with patient representatives. I am working on innovations to improve patient care, such as individual survivorship care plans and patient decision aids for childhood cancer survivors. In addition, I focus on the improvement of the quality of care by developing outcome indicators to measure the quality of care, benchmark with other pediatric cancer centers and identify areas for improvement.

Supervisor of: Rebecca van Kalsbeek, Kim Teunenbroek and Selina van den Oever

Supervisor: Leontien Kremer

Key Publications:

Mulder RL, Kremer LCM, Hudson MM, Bhatia S, Landier W, Levitt G, Constine LS, Wallace WH, van Leeuwen FE, Ronckers CM, Henderson TO, Dwyer M, Skinner R, Oeffinger KC. Recommendations for breast cancer surveillance for female childhood and young adult cancer survivors given chest radiation: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group. The Lancet Oncology 2013;14:e621-629

Skinner R, Mulder RL, Kremer LCM, Hudson MM, Constine LS, Bardi E, Boekhout A, Borgmann-Staudt A, Brown MC, Cohn R, Dirksen U, Giwercman A, Ishiguro H, Jahnukainen K, Kenney LB, Loonen JJ, Meacham L, Neggers S, Nussey S, Petersen C, Shnorhavorian M, van den Heuvel MM, van Santen HM, Green DM. Recommendations for gonadotoxicity surveillance for male childhood, adolescent and young adult cancer survivors: A report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium. Lancet Oncology 2017;18:e75-e90.

van Dorp W,Mulder RL, Kremer LC, Hudson MM, van den Heuvel-Eibrink MM, van den Berg MH, Levine JM, van Dulmen-den Broeder E, di Iorgi N, Albanese A, Armenian SH, Bhatia S, Constine LS, Corrias A, Deans R, Dirksen U, Gracia CR, Hjorth L, Kroon L, Lambalk CB, Landier W, Levitt G, Leiper A, Meacham L, Mussa A, Neggers SJ, Oeffinger KC, Revelli A, van Santen HM, Skinner R, Toogood A, Wallace WH, Haupt R. Recommendations for Premature Ovarian Insufficiency Surveillance for Female Survivors of Childhood, Adolescent, and Young Adult Cancer: A Report From the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboration With the PanCareSurFup Consortium. Journal of Clinical Oncology 2016;34:3440-3450.

 Mulder RL, Hudson MM, Skinner R, Kremer LC. Health problems in survivors of childhood cancer: the need for international collaboration in long-term follow-up care. Future Oncology 2013;9:1667-1670

Verbruggen LC, Hudson MM, Bowers DC, Ronckers CM, Armstrong GT, Skinner R, Hoving EW, Janssens GO, van der Pal HJH, Kremer LCM, Mulder RL. Variations in screening and management practices for subsequent asymptomatic meningiomas in childhood, adolescent and young adult cancer survivors. J Neurooncol 2020;147(2):417-425.

  • Childhood cancer survivorship care during the COVID-19 pandemic

    • dec. 2022
    • , et al
    • Journal of Cancer Survivorship
  • Primary cardioprotection with dexrazoxane in patients with childhood cancer who are expected to receive anthracyclines

    • dec. 2022
    • Esmée C., de Baat, et al
    • The Lancet Child and Adolescent Health
  • Evaluating the feasibility, effectiveness and costs of implementing person-centred follow-up care for childhood cancer survivors in four European countries

    • nov. 2022
    • Rebecca J., Van Kalsbeek, et al
    • BMJ Open
  • Dexrazoxane for preventing or reducing cardiotoxicity in adults and children with cancer receiving anthracyclines

    • sep. 2022
    • Esmée C., de Baat, et al
    • Cochrane Database of Systematic Reviews
  • Hypothalamic-Pituitary and Other Endocrine Surveillance Among Childhood Cancer Survivors

    • sep. 2022
    • Laura, van Iersel, et al
    • Endocrine reviews
View all publications