Trials with medicinal products
ATRT01 (Atypical Teratoid Rhabdoid Tumors) Clinical study of two existing treatments for atypical teratoid/rhabdoid tumors (ATRT) - open for inclusion
Dabrafenib (low grade/high grade glioma) Clinical study of the effect of dabrafenib in combination with trametinib in children and adolescents with a low grade or high grade glioma carrying a BRAF V600 mutation - closed for inclusion
Dabrafenib Roll-over CDRB436G2401 (low grade and high grade glioma) Clinical study to assess long-term effect in pediatric patients treated with dabrafenib and/or trametinib - open for inclusion
ESMART (different tumor types) Clinical study in children with cancer into the safety and efficacy of drugs matching a specific DNA alteration in the tumor - open for inclusion
HIT-HGG-2013 (High grade glioma) Clinical study of a new treatment for high-grade gliomas - open for inclusion
HR-MB (high-risk medulloblastoma) An international prospective trial on clinically high-risk medulloblastoma in patients older than 3 years - open for inclusion
INFORM2 NivEnt (various solid tumors) Clinical study with nivolumab and entinostat in children and young adults with refractory cancer - open for inclusion
LOGGIC/FIREFLY-2 (pediatric low-grade glioma) Clinical study of DAY101 in children, adolescent, and young adult patients with pediatric low-grade glioma (pLGG) with an abnormality in RAF (RAF alteration) - open for inclusion
LOXO-TRK-15003 (solid/CNS tumors) Clinical study of the safety and efficacy of the drug LOXO-101 (larotrectinib) in children with advanced solid tumors or primary central nervous system tumors - closed for inclusion
PNOC022; DMG-Act (diffuse midline gliomas) Clinical study of a new treatment of diffuse midline gliomas - open for inclusion
Ponatinib INCB084344 (leukemia/solid tumors) Clinical study of the safety and efficacy of ponatinib for the treatment of different types of leukemia or solid tumors in children - open for inclusion
Other trials
5-ALA (supratentorial brain tumors) Clinical study of improving the visualization of brain tumors with 5-ALA - open for inclusion
DIPG/DMG Registry (brainstem tumors) Clinical study into the development and treatment of tumors in and around the brainstem open for inclusion
DRUG Access protocol (solid tumors) A national protocol to facilitate access to new anti-cancer drugs and collect data from targeted anti-cancer drugs not yet eligible for reimbursement - open for inclusion
FOCUS Clinical study to optimize dosing of fluconazole in children for the prevention or treatment of invasive fungal infections - open for inclusion
LOGGIC Core (low-grade glioma) Clinical study into the development and course of low-grade glioma in children through extensive collection of data - open for inclusion
Nordic CMS (brain tumors) Clinical study into the problems with speaking after surgery for a tumor in the brain or brainstem - open for inclusion
PINOCCHIO (multiple types of cancer) Clinical study in children on the metabolism, distribution and excretion of chemotherapy in the body, also called pharmacokinetics - open for inclusion
SIMBA study (brain tumor) Observational study to investigate the relation between cognitive performance and MRI parameters in children who have been treated for a tumor in the posterior fossa - open for inclusion
Tumor donation in Childhood Cancer patients This study is designed to enable post-mortem tumor donation in children that die from all different types of pediatric solid and brain tumors, to enable research on end-stage disease - open for inclusion