Our website uses cookies. We use cookies to remember settings and to help provide you with the best experience we can. We also use cookies to continuously improve our website by compiling visitor statistics. Read more about cookies

Brain tumor

Here you will find summaries of a selection of ongoing clinical trials on brain tumors.

Trials with medicinal products

Dabrafenib (low grade/high grade glioma)  Clinical study of the effect of dabrafenib in combination with trametinib in children and adolescents with a low grade or high grade glioma carrying a BRAF V600 mutation - closed for inclusion

ESMART (different tumor types) Clinical study in children with cancer into the safety and efficacy of drugs matching a specific DNA alteration in the tumor - open for inclusion

INFORM2 NivEnt (various solid tumors)  Clinical study with nivolumab and entinostat in children and young adults with refractory cancer - open for inclusion

LOXO-TRK-15003 (solid/CNS tumors)  Clinical study of the safety and efficacy of the drug LOXO-101 (larotrectinib) in children with advanced solid tumors or primary central nervous system tumors - open for inclusion

Ponatinib INCB084344 (leukemia/solid tumors)  Clinical study of the safety and efficacy of ponatinib for the treatment of different types of leukemia or solid tumors in children - open for inclusion

Other trials

PINOCCHIO (multiple types of cancer)  Clinical study in children on the metabolism, distribution and excretion of chemotherapy in the body, also called pharmacokinetics - open for inclusion

SIMBA study (brain tumor)  Observational study to investigate the relation between cognitive performance and MRI parameters in children who have been treated for a tumor in the posterior fossa - open for inclusion