Trials with medicinal products
Dabrafenib (low grade/high grade glioma) Clinical study of the effect of dabrafenib in combination with trametinib in children and adolescents with a low grade or high grade glioma carrying a BRAF V600 mutation - closed for inclusion
ESMART (different tumor types) Clinical study in children with cancer into the safety and efficacy of drugs matching a specific DNA alteration in the tumor - open for inclusion
INFORM2 NivEnt (various solid tumors) Clinical study with nivolumab and entinostat in children and young adults with refractory cancer - open for inclusion
LOXO-TRK-15003 (solid/CNS tumors) Clinical study of the safety and efficacy of the drug LOXO-101 (larotrectinib) in children with advanced solid tumors or primary central nervous system tumors - open for inclusion
Ponatinib INCB084344 (leukemia/solid tumors) Clinical study of the safety and efficacy of ponatinib for the treatment of different types of leukemia or solid tumors in children - open for inclusion
Other trials
PINOCCHIO (multiple types of cancer) Clinical study in children on the metabolism, distribution and excretion of chemotherapy in the body, also called pharmacokinetics - open for inclusion
SIMBA study (brain tumor) Observational study to investigate the relation between cognitive performance and MRI parameters in children who have been treated for a tumor in the posterior fossa - open for inclusion